JAMA - Opioid overdose crisis is expected to worsen in the United States

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JAMA - Opioid overdose crisis is expected to worsen in the United States

JAMA Network
Original Investigation Substance - Use and Addiction
Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States
Qiushi Chen, PhD1,2,3; Marc R. Larochelle, MD, MPH4; Davis T. Weaver, BS2,5; et al
Published: February 1, 2019. doi:10.1001/jamanetworkopen.2018.7621

Question 
What is the projected effect of lowering incident nonmedical prescription opioid use on the future trajectory of the opioid overdose crisis in the United States?

Findings In this system dynamics model study, under current conditions, the opioid overdose crisis is expected to worsen—with the annual number of opioid overdose deaths projected to reach nearly 82 000 by 2025, resulting in approximately 700 000 deaths from 2016 to 2025. Interventions focused on lowering the incidence of prescription opioid misuse were projected to result in a 3.0% to 5.3% decrease in opioid overdose deaths over this period.

Meaning Prevention of prescription opioid misuse alone is projected to have a modest effect on lowering opioid overdose deaths in the near future, and multipronged approach is needed to dramatically change the course of the epidemic.



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