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Hepatitis C Symptoms Can Persist After Cure Cryoglobulins observed 2 years after sustained virologic response

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Hepatitis C Symptoms Can Persist After Cure Cryoglobulins observed 2 years after sustained virologic response

by Ed Susman, Contributing Writer, MedPage Today April 13, 2018

PARIS – Long after hepatitis C virus has been eradicated by direct acting antiviral therapy, manifestations of the disease persist and can relapse with potentially deadly consequences, researchers suggested here.

Despite having achieved a sustained virologic response to therapy, 10% of symptomatic cryoglobulinemic vasculitis still had relapses of symptoms of their disease, said Martin Bonacci, MD, a hepatologist at the Liver and Digestive Diseases Networking Biomedical Research Centre in Barcelona.

"Clinical and particularly immunological response improves significantly over time after hepatitis C virus cure in symptomatic and asymptomatic patients," Bonacci said in his presentation at the International Liver Congress, sponsored by the European Association for the Study of the Liver. "However, 2 years after hepatitis C virus elimination cryoglobulinemia may persist and clinical relapse may occur in a small proportion of patients, suggesting that a longer monitoring of these patients is still warranted."
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