Titre : New Study: Acetaminophen Safety During Flu Season
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New Study: Acetaminophen Safety During Flu Season
New Study: Acetaminophen Safety During Flu Season
During the flu season we all reach for medications to elevate our symptoms, with so many over the counter choices containing the active ingredient acetaminophen, its no wonder we might be taking more than the recommended daily dose.
This is especially dangerous for people who go undiagnosed with liver disease. In the US nonalcoholic fatty liver disease (NAFLD), is projected to surpass viral hepatitis as the leading cause of liver transplantation, but most people don't even know they have it. Sound familiar? The same can be said for nearly half the people with hepatitis C, because new infections go undiagnosed as well.
In a new study headed up by Saul Shiffman, Ph.D, published in the March issue of British Journal of Clinical Pharmacology, the good doctor found during flu season acetaminophen overdosing increases. A link to the research article is provided below, however, I highly suggest you read the following patient-friendly overview, written by Dennis Thompson; Fighting a Cold or Flu? Beware of Overdosing on Tylenol. Thompson breaks down the study, along with interviewing experts on the importance of using acetaminophen; in both healthy people, and those with liver disease, cirrhosis, or on a transplant list.
ORIGINAL ARTICLE
Prevalence of Exceeding Maximum Daily Dose of Acetaminophen, and Seasonal Variations in Cold-Flu Season
Published March 8, 2018 in British Journal of Clinical Pharmacology
Download PDF
Published March 8, 2018 in British Journal of Clinical Pharmacology
Download PDF
What is known about this subject
• Acetaminophen is an active ingredient in many prescription and over-the-counter (OTC) medications.
• When taken in high doses, acetaminophen can cause liver injury.
• Users sometimes exceed the maximum recommended dose of 4 grams per day.
What this study adds
What this study adds
• Over the course of 7 days, 6.3% of acetaminophen users exceed 4 grams on at least one day.
• Such over-dose occurred more often in cold-flu season (6.5%) than in off-season (5.3%), due to increased use of OTC combinations treating upper-respiratory cold/flu symptoms.
Complete Research Article - http://onlinelibrary.wiley.com/doi/10.1111/bcp.13551/epdf
Tylenol & Viral Hepatitis
Experts suggest even for healthy people, a safe practice is to take only what you need, and to not exceed 3,000 mg a day if at all possible. As for people with HCV, the following document defines acetaminophen use for people; with or without cirrhosis.
Tylenol & Viral Hepatitis
Experts suggest even for healthy people, a safe practice is to take only what you need, and to not exceed 3,000 mg a day if at all possible. As for people with HCV, the following document defines acetaminophen use for people; with or without cirrhosis.
The maximum dose of acetaminophen that adults can safely take over a 24-hour period is four grams, which equals eight extra-strength pills or about 12 regular-strength pills. (An extra-strength pill contains 500 mg and a regular strength pill contains 325 mg).
Thus articles New Study: Acetaminophen Safety During Flu Season
that is all articles New Study: Acetaminophen Safety During Flu Season This time, hopefully can provide benefits to you all. Okay, see you in another article post.
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