Titre : Treatment of hepatitis C in special populations
link : Treatment of hepatitis C in special populations
Treatment of hepatitis C in special populations
Journal of Gastroenterology
pp 1–15
pp 1–15
Review
First Online: 03 January 2018
First Online: 03 January 2018
Treatment of hepatitis C in special populations
Goki Suda, Koji Ogawa, Kenichi Morikawa, Naoya Sakamoto
Abstract
Hepatitis C virus (HCV) infection is one of the primary causes of liver cirrhosis and hepatocellular carcinoma. In hemodialysis patients, the rate of HCV infection is high and is moreover associated with a poor prognosis. In liver transplantation patients with HCV infection, recurrent HCV infection is universal, and re-infected HCV causes rapid progression of liver fibrosis and graft loss.
Additionally, in patients with HCV and human immunodeficiency virus (HIV) co-infection, liver fibrosis progresses rapidly. Thus, there is an acute need for prompt treatment of HCV infection in these special populations (i.e., hemodialysis, liver transplantation, HIV co-infection). However, until recently, the standard anti-HCV treatment involved the use of interferon-based therapy.
In these special populations, interferon-based therapies could not achieve a high rate of sustained viral response and moreover were associated with a higher rate of adverse events. With the development of novel direct-acting antivirals (DAAs), the landscape of anti-HCV therapy for special populations has changed dramatically. Indeed, in special populations treated with interferon-free DAAs, the sustained viral response rate was above 90%, with a lower incidence and severity of adverse events.
Full Text
Thus articles Treatment of hepatitis C in special populations
that is all articles Treatment of hepatitis C in special populations This time, hopefully can provide benefits to you all. Okay, see you in another article post.
You are now reading the article Treatment of hepatitis C in special populations the link address https://newsaninpiration.blogspot.com/2018/01/treatment-of-hepatitis-c-in-special.html
0 Response to "Treatment of hepatitis C in special populations"
Post a Comment