Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry - Hallo friend NEWS AN INSPIRATION, In the article you read this time with the title Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry, we have prepared well for this article you read and download the information therein. hopefully fill posts Article ECONOMY, Article HEALTH, Article POLITICS, Article SPORTS, Article TRAVELING, Article UPDATE, we write can understand. Well, happy reading.

Titre : Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry
link : Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry

Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry

Liver transplantation for chronic hepatitis C virus infection in the United States 2002–2014: An analysis of the UNOS/OPTN registry
Georg Dultz, Barry I. Graubard, Paul Martin, Martin-Walter Welker, Johannes Vermehren, Stefan Zeuzem, Katherine A. McGlynn , Tania M. Welzel
Published: October 31, 2017 http://ift.tt/2ylkVaI

Full-Text
View Online
Download PDF

Abstract
Chronic hepatitis C virus (HCV) infection is a leading cause for orthotopic liver transplantation (OLT) in the U.S. We investigated characteristics of HCV-infected patients registered for OLT, and explored factors associated with mortality. Data were obtained from the United Network for Organ Sharing and Organ Procurement and Transplantation network (UNOS/OPTN) registry. Analyses included 41,157 HCV-mono-infected patients ≥18 years of age listed for cadaveric OLT between February 2002 and June 2014. Characteristics associated with pre- and post-transplant survival and time trends over the study period were determined by logistic and Cox proportional hazard regression analyses and Poisson regressions. Most patients were white (69.1%) and male (70.8%). At waitlist registration, mean age was 54.6 years and mean MELD was 16. HCC was recorded in 26.9% of the records. A total of 51.2% of the patients received an OLT, 21.0% died or were too sick; 15.6% were delisted and 10.4% were still waiting. Factors associated with increased waitlist mortality were older age, female gender, blood type 0, diabetes, no HCC and transplant region (p<0.001). OLT recipient characteristics associated with increased risk for post OLT mortality were female gender, age, diabetes, race (p<0,0001), and allocation MELD (p = 0.005). Donor characteristics associated with waitlist mortality included age, ethnicity (p<0.0001) and diabetes (p<0.03). Waitlist registrations and OLTs for HCC significantly increased from 14.4% to 37.3% and 27.8% to 38.5%, respectively (p<0.0001). Pre- and post-transplant survival depended on a variety of patient-, donor-, and allocation- characteristics of which most remain relevant in the DAA-era. Still, intensified HCV screening strategies and timely and effective treatment of HCV are highly relevant to reduce the burden of HCV-related OLTs in the U.S.

http://ift.tt/2lCHG41

Thus articles Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry

that is all articles Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry This time, hopefully can provide benefits to you all. Okay, see you in another article post.

You are now reading the article Liver transplantation for HCV in the United States 2002–2014: An analysis of the UNOS/OPTN registry the link address https://newsaninpiration.blogspot.com/2017/11/liver-transplantation-for-hcv-in-united.html

Tweet

Subscribe to receive free email updates: