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Titre : Clinical improvement after successful antiviral DAA therapy for hepatitis C
link : Clinical improvement after successful antiviral DAA therapy for hepatitis C

Clinical improvement after successful antiviral DAA therapy for hepatitis C

Follow-up of sustained virologic responders with hepatitis C and advanced liver disease after interferon/ribavirin - free treatment

Karin Kozbial 1 , Stephan Moser 2 , Ramona Al - Zoairy 3 , Remy Schwarzer 4 , Christian Datz 5 , Rudolf Stauber 6 , Hermann Laferl 7 , Michael Strasser 8 , S andra Beinhardt 1 , Albert Friedrich Stättermayer 1 , Michael Gschwantler 2 , H einz Zoller 3 , Andreas Maieron 4 ,9 , Ivo Graziadei 10 , Michael Trauner 1 , P etra Steindl - Munda 1 , Harald Hofer 1, 11 , P eter Ferenci

doi: 10.1111/liv.13629

Link To Article: http://ift.tt/2zQi1u9
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Key points

SVR is durable irrespective of the interferon - free DAA regimen used. 
Survival was excellent for patients with F3 and Child - Pugh A cirrhosis. 
Decompensation before or at baseline was significantly associated with decompensation and with death during follow-up . 
Despite successful therapy a risk of hepatocellular carcinoma remains among patients with cirrhosis, necessitating a regular follow-up

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