Titre : Use of DAAs in the management of HCV in the liver transplantation setting
link : Use of DAAs in the management of HCV in the liver transplantation setting
Use of DAAs in the management of HCV in the liver transplantation setting
In Case You Missed ItInfectious Disease Advisor
Management of HCV in Liver Transplant Candidates and Recipients
July 05, 2017
Infectious Disease Advisor had the opportunity to discuss the use of DAAs in the management of HCV in the liver transplantation setting with Leslie B. Lilly, MD, FRCPC, medical director, GI Transplantation, and assistant professor of medicine, Toronto General Hospital, Ontario, Canada. Dr Lilly was part of the working group that developed the International Liver Transplantation Society consensus statements.
Infectious Disease Advisor: What is your perspective on using antiviral therapy to treat HCV in a candidate for liver transplant? Are there any benefits or risks?
Leslie B. Lilly, MD, FRCPC: In general, patients infected with hepatitis C should be treated early enough in their disease course that progression to cirrhosis, liver failure, and liver cancer can be avoided. Patients with cirrhosis who show no signs of liver failure or who have mild signs may benefit from treatment and avoid liver transplantation. Patients referred and listed with very advanced disease are less likely to benefit, and treatment should be deferred until after transplantation. Where the line is drawn is still debated, and it is important that the treating physician is in communication with the transplant program as that decision is made.
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